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28)Republic Day Parade 2019: Indias rich cultural diversity with display at Rajpath; 10 tips

India Republic Day -- On Indias 70th Republic Moment Saturday the annual celebration in the national capital exhibited the countrys rich ethnic heritage and traditions. Typically the central theme of the tableaux displayed was Mahatma Gandhi as 2019 marks all four of his 150th labor and birth anniversary. The might from the Indian military was in full display and in certain womens power. Before the celebration celebrations kicked off using Prime Minister Narendra Modi paying homage to the martyrs by laying a flower wreath at Amar Jawan Jyoti. At Rajpath the Prime Minister received President Ram memory Nath Kovind and South Africas President Cyril Ramaphosa who was the Chief Guest at Indias Republic Day 2019 event. President Kovind hoisted the tricolour as the nationwide anthem played and a 21-gun salute was fired by seven cannons of 2281 Field Regiment. Republic Moment Parade 2019 * Assam Rifles tableau: Participating in the particular Republic Day parade the first time in history
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Bone marrow

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Bone marrow is a semi-solid tissue found within the spongy or cancellous portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production or haematopoiesis. It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells. In adult humans, bone marrow is primarily located in the ribs, vertebrae, sternum, and bones of the pelvis. Bone marrow comprises approximately 5% of total body mass in healthy adult humans, such that a man weighing 73 kg (161 lbs) will have around 3.65 kg (8 lbs) of bone marrow. Human marrow produces approximately 500 billion blood cells per day, which join the systemic circulation via permeable vasculature sinusoids within the medullary cavity. All types of hematopoietic cells, including both myeloid and lymphoid lineages, are created in bone marrow; however, lymphoid cells must migrate to other lymphoid organs (e.g. thymus) in order to complete maturation. Bone marrow transplants can be conducted to
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Structure

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The composition of marrow is dynamic, as the mixture of cellular and non-cellular components (connective tissue) shifts with age and in response to systemic factors. In humans, marrow is colloquially characterized as "red" or "yellow" marrow (Latin: medulla ossium rubra , Latin: medulla ossium flava , respectively) depending on the prevalence of hematopoietic cells vs fat cells. While the precise mechanisms underlying marrow regulation are not understood, compositional changes occur according to stereotypical patterns. For example, a newborn baby's bones exclusively contain hematopoietically active "red" marrow, and there is a progressive conversion towards "yellow" marrow with age. In adults, red marrow is found mainly in the central skeleton, such as the pelvis, sternum, cranium, ribs, vertebrae and scapulae, and variably found in the proximal epiphyseal ends of long bones such as the femur and humerus. In circumstances of chronic hypoxia,
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Function

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Mesenchymal stem cells edit The bone marrow stroma contains mesenchymal stem cells (MSCs), also known as marrow stromal cells. These are multipotent stem cells that can differentiate into a variety of cell types. MSCs have been shown to differentiate, in vitro or in vivo, into osteoblasts, chondrocytes, myocytes, marrow adipocytes and beta-pancreatic islets cells. Bone marrow barrier edit The blood vessels of the bone marrow constitute a barrier, inhibiting immature blood cells from leaving the marrow. Only mature blood cells contain the membrane proteins, such as aquaporin and glycophorin, that are required to attach to and pass the blood vessel endothelium. Hematopoietic stem cells may also cross the bone marrow barrier, and may thus be harvested from blood. Lymphatic role edit The red bone marrow is a key element of the lymphatic system, being one of the primary lymphoid organs that generate lymphocytes from immature hematopoietic progenitor cells. The bone marrow and thymus constit
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As food

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Animal bone marrow has been used in cuisine worldwide for millennia, such as the famed Milanese Ossobuco. citation needed
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Clinical significance

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Disease edit The normal bone marrow architecture can be damaged or displaced by aplastic anemia, malignancies such as multiple myeloma, or infections such as tuberculosis, leading to a decrease in the production of blood cells and blood platelets. The bone marrow can also be affected by various forms of leukemia, which attacks its hematologic progenitor cells. Furthermore, exposure to radiation or chemotherapy will kill many of the rapidly dividing cells of the bone marrow, and will therefore result in a depressed immune system. Many of the symptoms of radiation poisoning are due to damage sustained by the bone marrow cells. To diagnose diseases involving the bone marrow, a bone marrow aspiration is sometimes performed. This typically involves using a hollow needle to acquire a sample of red bone marrow from the crest of the ilium under general or local anesthesia. Application of stem cells in therapeutics edit Bone marrow derived stem cells have a wide array of application in regenera
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Fossil record

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The earliest fossilised evidence of bone marrow was discovered in 2014 in Eusthenopteron , a lobe-finned fish which lived during the Devonian period approximately 370 million years ago. Scientists from Uppsala University and the European Synchrotron Radiation Facility used X-ray synchrotron microtomography to study the fossilised interior of the skeleton's humerus, finding organised tubular structures akin to modern vertebrate bone marrow. Eusthenopteron is closely related to the early tetrapods, which ultimately evolved into the land-dwelling mammals and lizards of the present day.
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